What Are the Long-Term Risks of Using Depo-Provera?

Depo-Provera, a contraceptive injection, is known for its convenience and effectiveness in preventing pregnancy. However, long-term use of Depo-Provera carries certain health risks that should be carefully considered. Recently, concerns have emerged regarding a risk of developing meningioma, a type of brain tumor, in those using Depo-Provera.

If you or a loved one have been affected, contact a Depo-Provera lawsuit lawyer for a free case evaluation to understand your options and protect your rights. Our law firm is actively reviewing cases involving Depo-Provera and its association with meningioma brain tumors as part of a mass tort effort.

Depo-Provera Is Linked to Brain Tumors

In a recent study published in the British Medical Journal (BMJ), a French research group found a link between medroxyprogesterone acetate and meningiomas. In their study group of 18,000 women who underwent surgery for a meningioma, those who were long-time users of Depo Provera had a 5.6 times greater chance of developing the brain tumor.

Meningiomas are intracranial tumors. They grow within the meninges of the brain and spinal cord. Though benign in nature, they do apply pressure on the surrounding tissues and can cause such symptoms as: 

• Headaches
• Seizures
• Vision problems, including loss of vision
• Hearing issues, including hearing loss
• Cognitive difficulties 
• Speech impairments 

In addition to these symptoms of meningiomas, long-term use of Depo Provera has other potentially common side effects. 

Long-Term Risks of Using Depo‐Provera

According to Cleveland Clinic, below are the other potential long-term health risks and medical conditions associated with the injectable contraceptive Depo-Provera:

Bone Density Loss

One of the most widely recognized long-term risks of using Depo-Provera is its potential to decrease bone mineral density. The injection lowers estrogen levels, a hormone essential for maintaining strong bones.

Over time, this can result in a loss of bone minerals or an increased risk of osteoporosis, especially in women who use the injection over several years. Because of this risk, Pfizer and many health professionals advise limiting Depo-Provera use to two years or less if other birth control options are available and suitable.

Irregular Menstrual Bleeding and Amenorrhea

Many Depo-Provera users experience changes in their menstrual cycle, including spotting, irregular bleeding, or a complete absence of periods (amenorrhea).

For some, these side effects lessen with time; for others, they can persist throughout use. While amenorrhea itself is not typically harmful, the unpredictability of bleeding can be a significant inconvenience for some users.

According to medical sources, nearly 50% of women using Depo-Provera report experiencing amenorrhea within the first year of use. While many adjust to these changes, some may find that the unpredictability of menstrual changes is a reason to discontinue use.

Cancer and Cardiovascular Risks

While research is ongoing, some studies suggest a potential link between Depo-Provera use and an increased risk of breast cancer in certain groups.

Some research also suggests an association between prolonged Depo-Provera use and an increased risk of cardiovascular problems, especially in women with pre-existing risk factors like smoking or high blood pressure.

Potential Delay in Fertility Return

Unlike some other birth control methods, Depo-Provera can result in a delayed return to fertility after discontinuation. While this delay varies among individuals, it can take several months to over a year for normal ovulation and menstrual cycles to resume after stopping the injections.

This factor is essential for women considering Depo-Provera as a short-term option.

Weight Gain and Loss

Fluctuation in weight is a common concern among Depo-Provera users. According to the manufacturer, Pfizer, on average, women may gain around 5-10 pounds within the first couple of years of use, though this amount can vary widely from person to person.

Unlike with some other contraceptive methods, the weight gained while using Depo-Provera may be more challenging to lose.

Mood Changes and Mental Health Concerns

Some Depo-Provera users report experiencing mood changes, depression, or anxiety. While it’s challenging to definitively link these symptoms to Depo-Provera alone, some studies suggest that the hormonal changes associated with the injection may impact the mood of some users, especially those with a history of depression or mental health concerns.

Final Considerations

Like any medication, Depo-Provera comes with potential risks, particularly with extended use. It’s essential to have regular consultations with a healthcare provider to weigh the benefits against any potential long-term effects.

Depo-Provera Brain Tumor Lawsuits

If you or a loved one has been affected by health complications potentially linked to meningioma brain tumors, you may qualify to file a lawsuit for the losses and injuries you have suffered. 

To meet the qualifications for a Depo Provera lawsuit, you must have used the hormonal birth control shot manufactured by any of the following pharmaceutical companies twice and been diagnosed with a meningioma: 

• Pfizer
• Pharmacia & Upjohn Company LLC
• Greenstone LLC
• A-S Medication Solutions
• Prasco Laboratories
• Preferred Pharmaceuticals Inc

If you meet these qualifications or have questions, our lawyers may be able to help.

Contact Chalik & Chalik Injury Lawyers Regarding Your Depo Provera Lawsuit

We encourage you to reach out to our law firm for a free case evaluation. The Depo Provera attorneys at Chalik & Chalik Injury lawyers are actively reviewing cases, and we can help provide the support you need in seeking justice and maximum compensation for your losses.

Call us today to get started and learn how we can help you get the results you deserve.