What Are the Long-Term Risks of Using Depo‐Provera?

Depo-Provera, a contraceptive injection, is known for its convenience and effectiveness in preventing pregnancy. However, long-term use of Depo-Provera carries certain health risks that should be carefully considered. Recently, concerns have emerged regarding a risk of developing meningioma, a type of brain tumor, in those using Depo-Provera. 

If you or a loved one have been affected, contact a Depo-Provera lawsuit lawyer from Chalik & Chalik for a free case evaluation to understand your options and protect your rights. Our firm is actively reviewing cases involving Depo-Provera and its association with meningioma brain tumors as part of a mass tort effort. 

Below, explore the other potential long-term health risks associated with Depo-Provera.

Long-Term Risks of Using Depo‐Provera

Bone Density Loss

One of the most widely recognized long-term risks of using Depo-Provera is its potential to decrease bone mineral density. The injection lowers estrogen levels, a hormone essential for maintaining strong bones.

Over time, this can result in thinning bones or an increased risk of osteoporosis, especially in women who use the injection over several years. Because of this risk, Pfizer and many health professionals advise limiting Depo-Provera use to two years or less if other birth control options are available and suitable.

Irregular Menstrual Bleeding and Amenorrhea

Many Depo-Provera users experience changes in their menstrual cycle, including spotting, irregular bleeding, or a complete absence of periods (amenorrhea).

For some, these side effects lessen with time; for others, they can persist throughout use. While amenorrhea itself is not typically harmful, the unpredictability of bleeding can be a significant inconvenience for some users.

According to medical sources, nearly 50% of women using Depo-Provera report experiencing amenorrhea within the first year of use. While many adjust to these changes, some may find that the unpredictability of menstrual changes is a reason to discontinue use.

Cancer & Cardiovascular Risks

While research is ongoing, some studies suggest a potential link between Depo-Provera use and an increased risk of breast cancer in certain groups.

Some research also suggests an association between prolonged Depo-Provera use and an increased risk of cardiovascular problems, especially in women with pre-existing risk factors like smoking or high blood pressure.

Potential Delay in Fertility Return

Unlike some other birth control methods, Depo-Provera can result in a delayed return to fertility after discontinuation. While this delay varies among individuals, it can take several months to over a year for normal ovulation and menstrual cycles to resume after stopping the injections.

This factor is essential for women considering Depo-Provera as a short-term option.

Weight Gain

Weight gain is a common concern among Depo-Provera users. Studies show that, on average, women may gain around 5-10 pounds within the first couple of years of use, though this amount can vary widely from person to person.

Unlike with some other contraceptive methods, the weight gained while using Depo-Provera may be more challenging to lose.

Mood Changes and Mental Health Concerns

Some Depo-Provera users report experiencing mood changes, depression, or anxiety. While it’s challenging to definitively link these symptoms to Depo-Provera alone, some studies suggest that the hormonal changes associated with the injection may impact mood for some users, especially those with a history of depression or mental health concerns.

Final Considerations

Like any medication, Depo-Provera comes with potential risks, particularly with extended use. It’s essential to have regular consultations with a healthcare provider to weigh the benefits against any potential long-term effects.

Depo-Provera Brain Tumor Lawsuits

If you or a loved one has been affected by health complications potentially linked to meningioma brain tumors, we encourage you to reach out to our attorneys for a free case evaluation.

Our team at Chalik & Chalik is actively reviewing cases, and we can help provide the support you need in seeking justice and maximum compensation for your losses.